Spotlight: Advancing Uric Acid Detection with a Novel g-C₃N₄@nZVI/CNT-Modified Electrode

ECS Sensors Plus is pleased to highlight a recent contribution that showcases the power of material innovation in enhancing electrochemical sensing technologies. In their new article, “Application of a g-C₃N₄@nZVI/CNTs Modified Carbon Paste Electrode for Uric Acid Detection in Spiked Urine Samples,” Aya A. Mouhamed, Ola G. Hussein, Maria Osama Mekhail, Tony Victor Zaki, Amr M. Mahmoud, and Jeffrey G. Bell present a promising approach for accurate, sensitive uric acid detection.

The research team developed a carbon paste electrode modified with a uniquely engineered g-C₃N₄@nZVI/CNT nanocomposite. By combining graphitic carbon nitride’s high surface area, nano zero-valent iron’s catalytic activity, and carbon nanotubes’ conductivity, the authors created a synergistic platform capable of boosting electron transfer and improving analytical performance.

(Click to enlarge)

Using differential pulse voltammetry, the sensor demonstrated a strong linear response (2.0–100.0 μM), a low detection limit (1.7 μM), and remarkable selectivity—even in the presence of common interferants. Its reliability, repeatability, and long-term stability underscore its potential for practical application.

Importantly, the modified electrode successfully detected uric acid in spiked urine samples, pointing to impactful uses in clinical diagnostics and environmental monitoring. This work highlights a scalable, cost-effective sensing strategy with strong translational potential.

Congratulations to the authors on this innovative contribution to the sensing community!

DISCLAIMER

All content provided in the ECS blog is for informational purposes only. The opinions and interests expressed here do not necessarily represent ECS's positions or views. ECS makes no representation or warranties about this blog or the accuracy or reliability of the blog. In addition, a link to an outside blog or website does not mean that ECS endorses that blog or website or has responsibility for its content or use.

ECS
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.