New paper-based, point-of-care diagnostic tools could lead to improvements in device cost, weight, and flexibility. The recently developed SPEDs, or self-powered, paper-based electrochemical device, can detect biomarkers such as glucose and white blood cells, all while remaining easy to read for non-experts.

The Purdue University research team behind this project believes it could be applicable for patients in regions where access to sophisticated medical equipment is limited.

“You could consider this a portable laboratory that is just completely made out of paper, is inexpensive and can be disposed of through incineration,” says Ramses V. Martinez, an assistant professor of industrial and biomedical engineering at Purdue University. “We hope these devices will serve untrained people located in remote villages or military bases to test for a variety of diseases without requiring any source of electricity, clean water, or additional equipment.”

CopperResearchers from MIT have developed a new way to extract copper by separating the commercially valuable metal from sulfide minerals in one step without harmful byproducts. The goal of this new process is to simplify metal production, thereby eliminating harmful byproducts and driving down costs.

To achieve this result, the team used a process called molten electrolysis. Electrolysis is a common technique used to break apart compounds, often seen in water splitting to separate hydrogen from oxygen. The same process is also used in aluminum production and as a final step in copper production to remove any impurities. However, electrolysis in copper production is a multistep process that emits sulfur dioxide.

This from MIT:

Contrary to aluminum, however, there are no direct electrolytic decomposition processes for copper-containing sulfide minerals to produce liquid copper.

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Fuel CellResearchers from Purdue University are making headway on solving issues in electrolyzers and fuel cell development by gaining new insight into electrocatalysts.

Electrocatalysts are key in promoting the chemical reactions that happen in both fuel cells and electrolyzers. However, while activating theses chemical reactions is crucial, the electrocatalysts tend to be unstable and can corrode when used in fuel cells and electrolyzers.

ECS member Jeffrey Greeley is looking to address this issue by identifying the structure for an active, stable electrocatalyst made of nickel nanoislands deposited on platinum.

“The reactions led to very stable structures that we would not predict by just looking at the properties of nickel,” Greeley says. “It turned out to be quite a surprise.”

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Periodic TableUsing high pressure, scientists have created the first high-entropy metal alloy made of common metals to have a hexagonal close-packed (HCP) atomic structure.

This makes it lighter and stronger than comparable metal alloys with different structures.

Traditional alloys typically consist of one or two dominant metals with a pinch of other metals or elements thrown in. Classic examples include adding tin to copper to make bronze, or carbon to iron to create steel.

In contrast, “high-entropy” alloys consist of multiple metals mixed in approximately equal amounts. The result is stronger and lighter alloys that are more resistant to heat, corrosion, and radiation, and that might even possess unique mechanical, magnetic, or electrical properties.

Despite significant interest from material scientists, high-entropy alloys have yet to make the leap from the lab to actual products. One major reason is that scientists haven’t yet figured out how to precisely control the arrangement, or packing structure, of the constituent atoms.

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HydrogenHydrogen has many highly sought after qualities when it comes to clean energy sources. It is a simple element, high in energy, and produces nearly zero harmful emissions. However, while hydrogen is one of the most plentiful elements in the universe, it does not occur naturally as a gas. Instead, we find it combined with other elements, like oxygen in the form of water. For many researchers, water-splitting has been a way to isolate hydrogen for use in cars, houses, and other sustainable fuels.

But water-splitting requires an effective catalyst to speed up chemical reactions, while simultaneously preventing the gasses to recombine. Researchers from the DOE’s SLAC National Accelerator Laboratory believe they may have the answer with the new development of a molybdenum coating that can potentially improve water-splitting.

“When you split water into hydrogen and oxygen, the gaseous products of the reaction are easily recombined back to water and it’s crucial to avoid this,” says Angel Garcia-Esparza, lead author of the study. “We discovered that a molybdenum-coated catalyst is capable of selectively producing hydrogen from water while inhibiting the back reactions of water formation.”

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By: Mohammad S. Jalali, Massachusetts Institute of Technology

ResearchFrom social to natural and applied sciences, overall scientific output has been growing worldwide – it doubles every nine years. The Conversation

Traditionally, researchers solve a problem by conducting new experiments. With the ever-growing body of scientific literature, though, it is becoming more common to make a discovery based on the vast number of already-published journal articles. Researchers synthesize the findings from previous studies to develop a more complete understanding of a phenomenon. Making sense of this explosion of studies is critical for scientists not only to build on previous work but also to push research fields forward.

My colleagues Hazhir Rahmandad and Kamran Paynabar and I have developed a new, more robust way to pull together all the prior research on a particular topic. In a five-year joint project between MIT and Georgia Tech, we worked to create a new technique for research aggregation. Our recently published paper in PLOS ONE introduces a flexible method that helps synthesize findings from prior studies, even potentially those with diverse methods and diverging results. We call it generalized model aggregation, or GMA.

Pulling it all together

Narrative reviews of the literature have long been a key component of scientific publications. The need for more comprehensive approaches has led to the emergence of two other very useful methods: systematic review and meta-analysis.

In a systematic review, an author finds and critiques all prior studies around a similar research question. The idea is to bring a reader up to speed on the current state of affairs around a particular research topic.

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Websites of Note

By: Alice H. Suroviec, Berry College

Websites of NoteWolfram|Alpha

Wolfram|Alpha is a computational search engine that uses an extensive collection of built-in data and algorithms to answer computation questions using a web-browser interface. It is a free website designed by the programmers behind the Mathematica software package.
www.wolframalpha.com

NREL MatDB

NRELMatDB is a computational materials database that primarily contains information on materials for renewable energy applications such as photovoltaic materials, and materials for photo-electrochemical water splitting. This website is a growing collection of computed properties of stoichiometric and fully ordered materials. It is a very useful database for those needing comparative data.
NREL (National Renewable Energy Laboratory)
www.materials.nrel.gov

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By: Jens Blotevogel, Colorado State University

Solar fieldWithout knowing it, most Americans rely every day on a class of chemicals called per- and polyfluoroalkyl substances, or PFASs. These man-made materials have unique qualities that make them extremely useful. They repel both water and grease, so they are found in food packaging, waterproof fabric, carpets and wall paint. The Conversation

PFASs are also handy when things get heated. Consumers value this property in nonstick frying pans. Government agencies and industry have used them for decades to extinguish fires at airports and fuel storage facilities.

However, widespread use of PFASs has led to extensive contamination of public water systems. Today, these substances can be found in the blood serum of almost all U.S. residents. Exposure to PFASs has been linked to kidney and testicular cancer, as well as developmental, immune, hormonal and other health issues.

But removing them from the environment is not easy. Chemical bonds between fluorine and carbon – the backbone of PFAS molecules – are extremely strong. PFASs can be removed from water by filtering them out, but the used filters have to be disposed of afterwards, and landfilling only transfers the problem to another location. The best solution to the problem is to break down PFASs completely – and on that score, we’re making progress.

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Quantum dotsTiny crystals called quantum dots are used in LCD TVs to enhance color and image quality. A few years ago, scientists discovered a new type of crystal called nanoplatelets.

Like quantum dots, these two-dimensional structures are just a few nanometers in size, but have a more uniform flat, rectangular shape. They are extremely thin, often just the width of a few atomic layers, giving the platelets one of their most striking properties—their extremely pure color.

Now scientists have solved the mystery of out how these platelets form—and then created them in the lab using pyrite.

“We now know that there’s no magic involved in producing nanoplatelets, just science,” says David Norris, a materials engineering professor at ETH Zurich.

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By: Bruce Weinberg, The Ohio State University

Science funding is intended to support the production of new knowledge and ideas that develop new technologies, improve medical treatments and strengthen the economy. The idea goes back to influential engineer Vannevar Bush, who headed the U.S. Office of Scientific Research and Development during World War II. And the evidence is that science funding does have these effects. The Conversation

But, at a practical level, science funding from all sources supports research projects, the people who work on them and the businesses that provide the equipment, materials and services used to carry them out. Given current proposed cuts to federal science funding – the Trump administration has, for instance, proposed a 20 percent reduction for the National Institutes of Health – it’s important to know what types of people and businesses are touched by sponsored research projects. This information provides a window into the likely effects of funding cuts.

Most existing research into the effects of science funding tries to quantify research artifacts, such as publications and patents, rather than tracking people. I’ve helped to start an emerging project called the UMETRICS initiative which takes a novel approach to thinking about innovation and science. At its core, UMETRICS views people as key to understanding science and innovation – people conduct research, people are the vectors by which ideas move around and, ultimately, people are one of the primary “products” of the research enterprise.

UMETRICS identifies people employed on scientific projects at universities and the purchases made to carry out those projects. It then tracks people to the businesses and universities that hire them, and purchases to the vendors from which they come. Since UMETRICS relies entirely on administrative data provided by member universities (now around 50), the U.S. Census Bureau and other naturally occurring data, there are no reporting errors, sample coverage concerns or burden for people. It covers essentially all federal research funding as well as some funding from private foundations.

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